ISSN 1662-4009 (online)

ey0019.3-3 | Thyroid hormone action | ESPEYB19

3.3. Extended absorption of liothyronine from poly-zinc-liothyronine: results from a phase 1, double-blind, randomized, and controlled study in humans

AM Dumitrescu , EC Hanlon , M Arosemena , O Duchon , M Ettleson , M Giurcanu , AC Bianco

Thyroid. 2022 Feb;32(2):196-205. doi: 10.1089/thy.2021.0304. Epub 2021 Dec 31. PMID: 34641706Brief Summary: This phase 1, double-blind, randomized, single-dose, placebo-controlled, crossover study compared pharmacokinetics, pharmacodynamics, incidence of adverse events, and sleep pattern between the routinely used L-triiodothyronine (LT3) and a newly developed metal-coordinated form of LT3 (pol...